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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde1e7c4fb17f77c26b8b51b18e69e8294b2be61b6f451faf5ec5f418f8c9dad' 
  AND token = '2FMSb/4xwIlQkE1hLTVfKTy/Iw2gauFW4Wgmo6vGUvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}