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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f26382f1d116c4e369d19d4247445ce4baca6b58d7f0e0830623721d27a2be' 
  AND token = 'JoSo8bl1D48SbHTAehAEOhtAsONiNLuWrN8snENlwtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}