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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d75575c00796928af5b796cb249f6e6afb387bb3d1fe7c34366a7f6f3eaec8' 
  AND token = 'RM8SVuQ2J+tTiwVe35cs7K3zEPh7KciCQUpwfhZfizQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}