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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0ff318e05fe0d25eab46b6e04378564a4ffda0e640478d0ada06a1aff1bd97' 
  AND token = 'sSZjxaG9jbgBn7HsFJgK/OJm5VB5Jx2Th8IBaGG0O9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}