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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8916745a9a40e3ffdaf290e9c8671bf01c21d27d5bcb657ed8e5775a8b71e132' 
  AND token = '6FLtpZxn2chjpJ24qi5H1WmWnpxLKXXZpa5SjQMc82E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}