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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e25057d2528fb19dcfc96b3d4553db19eba8df02d418d821123f7c7e9bda6e' 
  AND token = 'Xn9oMHKa6Uqt+5+q2kz/tkA4PtDWFaeZrkIuV5m9tPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}