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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399c143ebfd1da8a5c60c438535161abce32b78f9297df5430d207e90c68ad9f' 
  AND token = 'Xtpylsf537Ol4iVWzBbvBbOGGXIM42EmBcshUO2Sk+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}