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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6002c01da7c4dfa4cea83762afd6418f038a452b3268538f3d45fdc6c6f2507' 
  AND token = 'Gj/z7J5Wh/sIx0/xalIm4g5vyowHfZCUyEf/dmmsuZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}