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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a696f132bd606164a188481db11a95759ac4f6e07ad603f51e348ca4c72c1e1' 
  AND token = 'iRjCaFUAYmZxZpR0ntiA05IUBFYSCcKC8lAMw4Hi3LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}