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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9c58d188c168371f18fa2d40e12bc302a1e2ce43781d18c0d5c7b5b1697adb9' 
  AND token = 'JZI8Pnox7/NAe1wqjHVZdlay6ffisczEJ/StX0RNoCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}