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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2da7f1dc33a4c7e6e4ef2a3f2323700c6e9bb1d25f7c5366855972934f9c7a' 
  AND token = 'PWUhmqcxiuDQ5XfRthGL/XcQzJAxcQFtOeCSwHE+/no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}