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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd2ef8a38e959c0a83b06ca94652d60b7ab541b8cf7e7792b1bfeca82db4d370' 
  AND token = 'VyY6T8sZgv+HcNahBTom/F6CH4RR2fg3DH3G2Wm0Hfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}