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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746d85b23120e4f259cfc16f1a4b71c0c4a9ba00fcdfcb74fc95fb39fe54feb2' 
  AND token = '/i0yjgAL1wl5ujPAfZI6RKM0SlRQXvTddE6nSlg2jUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}