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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2fcfb53fb9b22aed31c99ab1ce97b761faefdd8aa5852276bdb34c2c417fb65' 
  AND token = 'HQyva/h8pM2tcSUq0Sf/0W+XVOKD6o42sgBEB6fFhAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}