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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '594e1e5421c16a0640be244b9a89a2820a7bb2f390476dbf69701c7e0966f72e' 
  AND token = 'CTfwScsKO6luzOd+1B9BPkwHTrkPvzX57MkAaeYdCmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}