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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0db7309b08e0492ec1d4a223e971a3f34fe5ec0306ece47b20422d999be45d64' 
  AND token = 'skAFELIBaSlliJIhChARtna38sOjeurBuE3U81B77a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}