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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6a10cdb0746dc6dec234c8f472d3e6bca028ee5b6bc8721edf6907773771d6' 
  AND token = 's2zXBWi7RsDv4n2qXPlfv1qHhqSj8SRJvDj7Io8jzM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}