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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff279f1077a6d7e8e392d06d2914224de91b063c2197c52c7517a71e6e66f841' 
  AND token = 'VRm/vAysOWjpc6Ip03+1wLKcgeysAz//mFFFb/wBzQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}