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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f55eb8541b1c6d86d21a7f832f941b536da63310327294fe63ba222bb86b0a4' 
  AND token = 'XY3pS9olgrHvyWYbjre412/7vgQNKWsF1UtB427hhPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}