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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ed5c9abb2f8f6da84ae1f4d71ca3b5cbdbe808b5d23d5f824265a56deac9d8' 
  AND token = '24FMTS8UBsJnRn6GoY8QuJXAZ6In+9NwoeVIe/W+8SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}