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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c663fbf39bd78ee852c9ca08660d2323ab8e49ecbb50eb10c87f019978bf58' 
  AND token = 'IMQCZT272GQLxR8A9r8FLVcZNUR78lLFd3W1LTGS9as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}