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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9273f6057d5444a9d38343475e7d3fa81064d6cefa4607f86c2ea7530d465ce9' 
  AND token = 'aNIEfK635WuRGWx7Rld2F34+99XTsCUPQeh7xQxq3Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}