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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27e0d85e401139740f2f7bbd10c25f8ec2f1fed7077573f4b0f574ce8f72017' 
  AND token = 'jfKNreTlWqd1t8ETZnA4UbL0yPeU6wKwCj1pQFyxKH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}