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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57935c98af942beb7e712b34a87f771530cd2cdece10b7b889f80b7db8042f94' 
  AND token = 'lWkz3v0WzTaqA/bX2CQkymMqMft+8EcQjLh/f9q7UEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}