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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d51b2727f9f2ff8a517902b27811c168a5f2775402aa3606dac52001db5dca' 
  AND token = 'uFVhquLXLURXP7jPt99xsy23vOu15k3Bm1B4dDZVdMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}