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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550d65600195e21da9614278a4e74060f0606d0f0ab4c104d6eeb83d7de200f4' 
  AND token = 'BbEheqt9P+WzlVbnBAJ1ygBeNwNO1VwMBpZyhAmbSw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}