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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99127e9159addbd62cbd96eab63b68fd78bbcddaa0ddaa219fa42e3f0fc06b57' 
  AND token = 'PPwX7caqzxlCKD/wxt+H7TyMFWM6SwfstrFCFG1SJqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}