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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c349b71bf655b117044511a4a2ea08e656a51765f3eb696e1d50e4e7bdae1e5' 
  AND token = 'qfjjqaCiD59tiQcY1nceIjOK22jeX38B0FLdL9RCYLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}