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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b744ea48dc9e18527930402c3fbe82d283ce852d4823c1d84e5a0b3c2a41fc' 
  AND token = 'DgJiBTYr0xIFboUn9VPqvCl9oh3cfOksVPach+eJeg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}