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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe7db378fb316437aa1f5b8038f40ea42d210da62acbc05e2692d1316c0e1dd' 
  AND token = 'DirJ1leiWgRXSSbXEOqaRBUZuqyd1aw9yWTsuxb0IdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}