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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4447534a378115112c9c7249aab94af2ae04adc1a1a9b9be7e0c4d3619cfbd48' 
  AND token = 'krYKIwU+Y2VUVSwWP80/n3GIrTeXAlS1Y6pkmwqgKiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}