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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd4df250ee14c94be91e9d5419b791ea9acbcfcddc2724ff94353f0659094707' 
  AND token = 'LX8etY4Z1+uj0YrvhI0ccYFr/43u2KuTQckTun1f0CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}