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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c150cd901696c553a065586f294f40e249d103a22a6cb504fc970eb8a70a7f9' 
  AND token = 'Iq3oeD0AGT6fFZRUqQN+A3KuwG5z3srADaXldWKtzv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}