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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3549333d54d29109cd6076bf3b76ec9d6f84f43e6a5cddda57a78f84dea10d4a' 
  AND token = 'Y5Ryrd7wmDn2KAAgAkP9zDwzftEiBgc3mrHEOY3Y4D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}