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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19189f71e0fc4832ceb8e284a3eef53291c144a8f2da99e4507b3cf4a0686b16' 
  AND token = 'c+SxiWzxkyFpEOaVRUwu4R+l8lgs4GIGPFFaIueHRjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}