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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f0bb8380ad62426666c344df95e9141188ba0c8b3ac0495dfa22f1d297e55a' 
  AND token = 'ldupN4ASNOmxkH70JXybF4kYnMIYovSBsN+DcCdZpP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}