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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14a1a7fd67404d0e11ed1768db7f4316bf3609d3b6b06dc0f3baa866090febb' 
  AND token = 'Nc8qwAxihB0mh/NnBpxo7JS4d9XtAjIz5TlHsD5OVog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}