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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf48fd5c1f6473e82cec3d18c5f5fe37cb210078fa72ec7c0071ddb18220b73' 
  AND token = 'GRxHX9Px6sZcaISYbFsjcO2xoPxFK0/2SCQcxZCYB+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}