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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6403c37925b950493113c1e14fac0dc0f194c842755ba35ae6c2ad86ec1b199' 
  AND token = 'EeI3xGAPLoW+yC5XmlCUmHbNqPzHi+Gr5Z2rGMh3SkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}