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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84dd16de28a29944860a34cda8efc15364d7a56a682133fe5e6815fb2ef92340' 
  AND token = '+5VEuibhoFVoUDtoi0Cw/v5njOO2+kc+M0FBZfBj3NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}