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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a08fc9cd8596f9812059b356d6c3bf623d28f1fe32d9dde49822d93e93f43160' 
  AND token = 'f2NRyqzpt4tU2nhjiawgcyDZFfi0SRaJa2FWL64yTAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}