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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73b26c848124fe7b18bf0ea1f7227172ddeaac3d69c34c8ceac06dd5139835f' 
  AND token = 'f6gDTNLrD31p4D56eEsGYEtbeQW8cf8O0WeJfoSGvZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}