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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca85ee8bd50de3a8fbd7e1c66302fd747189ada43296e4bbf7d559e8aba11086' 
  AND token = 'vsEaEVtOq6+aKn6kj/afNZpOFH3oyYccXPI5hUHyPp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}