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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e0560a3e2609188882b7da50b0f2eaf7f81c1a55f910bca998a56ad11b9746' 
  AND token = 'MJreIo7QqtbRNEmaL393WLuMQczMabudh+OC7ye7SK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}