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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ddf6395ca9a0c60d4e24e5ceee6969ea383fc27024394eb530548b5715569d3' 
  AND token = 'QFU2uPxg48VREdWFDB4mu/I3O04/QcH3STxl4vly3d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}