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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2127e5cf788aaf7aab248cdeec5238f8e119ff4484d3142ba1c1e1779a156af8' 
  AND token = 'GEB8yzZg9cUQngfg1Naw2+vPeWBNIncwCZ5RcHRsXbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}