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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fea58ee6a0be80687bf734560e3351e6618936b572001365c6e61877187942b' 
  AND token = 'z8n0ZRz+W9NeeECKTabUoyKIBXtTvhJvEU5OC9zybWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}