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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f900aa8f34883fe5bbe915c79453209834db7472242ff2b96a01f3bd5d1db58c' 
  AND token = 'A49Zegp+9qCq0X+tKpYSAI2pE/O91x0djgSf/b3ZT7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}