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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5f5dc85d81d7d4a5f465276ecb34beb9df5a4697e7c68090d80b066dcc16de' 
  AND token = 'wZtxan9BaW4WjnX/D+zvuXU3s0x+cmt/CmVa9RtUqbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}