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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed644a54fadcdab36ccd551089d8f9a7f4d7bd2d1c4e1ddabb3b0f015509270' 
  AND token = 'bCNOiyP4fPBd4oE1GeWxobqHP3G6QrOc7E4mw3cd4E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}